371754 | Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb

371754
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M, R Rb Polyclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      371754-50UL
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      Stocked 
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          Plastic ampoule 50 ul
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          Description
          OverviewRecognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.
          Catalogue Number371754
          Brand Family Calbiochem®
          References
          ReferencesWange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
          Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
          Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.
          Product Information
          FormLiquid
          FormulationIn 140 mM NaCl, 100 mM potassium phosphate, pH 7.0.
          PreservativeNone
          Applications
          Key Applications Immunoblotting (Western Blotting)
          Neutralization Studies
          Application NotesImmunoblotting (1:1000)
          Neutralization Studies (see comments)
          Application CommentsThe antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
          Biological Information
          Immunogena synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
          HostRabbit
          IsotypeIgG
          Species Reactivity
          • Human
          • Mouse
          • Rat
          Antibody TypePolyclonal Antibody
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          371754

          References

          Reference overview
          Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
          Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
          Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.

          Brochure

          Title
          Antibody Sourcebook!" Second Edition
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-August-2007 RFH
          ApplicationImmunoblotting (1:1000)
          Neutralization Studies (see comments)
          DescriptionProtein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunit proteins.
          HostRabbit
          Immunogena synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
          IsotypeIgG
          Specieshuman, mouse, rat
          FormLiquid
          FormulationIn 140 mM NaCl, 100 mM potassium phosphate, pH 7.0.
          PreservativeNone
          CommentsThe antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
          Storage ≤ -70°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Toxicity Standard Handling
          ReferencesWange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
          Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
          Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.