MAB3071 Anti-G Protein Goα Antibody, clone 1C

MAB3071
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB M Ascites Monoclonal Antibody
      Description
      Catalogue NumberMAB3071
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-G Protein Goα Antibody, clone 1C
      References
      Product Information
      FormatAscites
      Applications
      ApplicationAnti-G Protein Goα Antibody, clone 1C detects level of G Protein Goα & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern blot 1:1000.

      Labels a single protein band of 39 - 42 kDa in bovine and rat membranes.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenBovine brain Goalpha purified by the method of Sternweis and Robishaw (J. Biol. Chem. [1984] 259, 13806).
      Clone1C
      HostMouse
      SpecificityGoa. Strong reactivity with bovine (100%) and human (58%). Slight reactivity with guinea pig (24%) and rat (26%). Does not react with mouse. Specificity confirmed by Western blot versus bovine Galphat, rat Goalpha, rat Gialpha-1, Gialpha-2, rat Gialpha-3, bovine Gsalpha, and murine GoalphaA and GoalphaB
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GNAO1
      • DKFZp686O0962
      • G-ALPHA-o
      • GNAO
      Non-Reactive Species
      • Mouse
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P29777 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.| P09471 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.
      SIZE: 354 amino acids; 40087 Da
      SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
      DOMAIN: SwissProt: P29777
      SIMILARITY: SwissProt: P29777 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily. | P09471 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      References

      Reference overviewPub Med ID
      Involvement of Gα(olf) -expressing neurons in the vomeronasal system of Bufo japonicus.
      Hagino-Yamagishi K, Nakazawa H.
      The Journal of comparative neurology  519  3189-201  2011

      Show Abstract
      21618228 21618228

      Data Sheet

      Title
      Anti-G Protein Goalpha, clone 1C - Data Sheet

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies