195111 | Anti-BACE1, C-Terminal (485-501) Rabbit pAb

195111
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M, R Rb Polyclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      195111-100UL
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      Stocked 
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          Plastic ampoule 100 ul
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          Description
          OverviewRecognizes both the immature and mature forms of the BACE1 protein.
          Catalogue Number195111
          Brand Family Calbiochem®
          SynonymsAnti-B690
          References
          ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.
          Product Information
          FormLiquid
          FormulationUndiluted serum.
          PreservativeNone
          Applications
          Key Applications Immunoprecipitation
          Radioimmunoassay
          Immunoblotting (Western Blotting)
          Immunofluorescence
          Immunohistochemistry
          Application NotesImmunoblotting (1:500-1:1000)
          Immunofluorescence (1:200)
          Immunohistochemistry (see comments)
          Immunoprecipitation (3 µl/reaction)
          Radioimmunoassay (3-5 µl/reaction)
          Application CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
          Biological Information
          Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
          ImmunogenHuman
          HostRabbit
          IsotypeIgG
          Species Reactivity
          • Human
          • Mouse
          • Rat
          Antibody TypePolyclonal Antibody
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          195111

          References

          Reference overview
          Yan, R., et al. 2001. J. Biol. Chem. 276, 36788.

          Brochure

          Title
          Antibody Sourcebook!" Second Edition
          Alzheimer's Disease Brochure & Technical Guide
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-June-2007 RFH
          SynonymsAnti-B690
          ApplicationImmunoblotting (1:500-1:1000)
          Immunofluorescence (1:200)
          Immunohistochemistry (see comments)
          Immunoprecipitation (3 µl/reaction)
          Radioimmunoassay (3-5 µl/reaction)
          DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes both the immature and mature forms of BACE1.
          Backgroundβ-secretase has been identified as a novel membrane-bound aspartyl protease named BACE1 (β-site amyloid precursor protein cleaving enzyme 1). It is one of two endopeptidases that cleave the β-amyloid precursor protein (APP) resulting in the accumulation of the β-amyloid deposits involved in the development of Alzheimer's disease.
          HostRabbit
          Immunogen speciesHuman
          Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
          IsotypeIgG
          Specieshuman, mouse, rat
          FormLiquid
          FormulationUndiluted serum.
          PreservativeNone
          CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.