454202 8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem

454202
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₂H₁₈N₄O₃ 78033-08-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      454202-10MG
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          Plastic ampoule 10 mg
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          Description
          OverviewA cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50 = 4 µM).
          Catalogue Number454202
          Brand Family Calbiochem®
          Synonyms8-Methoxymethyl-IBMX
          References
          ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
          Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
          Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
          Product Information
          CAS number78033-08-6
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₂H₁₈N₄O₃
          Chemical formulaC₁₂H₁₈N₄O₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPDE 1
          Primary Target IC<sub>50</sub>4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          454202

          References

          Reference overview
          Jackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
          Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
          Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-August-2008 RFH
          Synonyms8-Methoxymethyl-IBMX
          DescriptionA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50 = 4 µM).
          FormWhite solid
          CAS number78033-08-6
          Chemical formulaC₁₂H₁₈N₄O₃
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityDMSO (5 mg/ml) or Ethanol (2 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
          Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
          Han, P., et al. 1989. J. Biol. Chem. 274, 22337.