251700 | 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem

251700
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      251700-5MG
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      Stocked 
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      Available
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          Plastic ampoule 5 mg
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          Description
          OverviewEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
          Catalogue Number251700
          Brand Family Calbiochem®
          Synonyms1,5-DNS-GGACK, 2HCl
          References
          ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
          Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
          Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
          Product Information
          ATP CompetitiveN
          FormOff-white solid
          ReversibleN
          Applications
          Application1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.
          Biological Information
          Primary TargetUPA
          Primary Target IC<sub>50</sub>100 nM for factor Xa
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          251700

          References

          Reference overview
          Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
          Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
          Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-June-2008 RFH
          Synonyms1,5-DNS-GGACK, 2HCl
          DescriptionEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
          FormOff-white solid
          SolubilityReconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.
          Storage +2°C to +8°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
          Toxicity Standard Handling
          ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
          Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
          Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.