407306 γ-Interferon, Human, Recombinant, E. coli

407306
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407306-100UG
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      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
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          Plastic ampoule 100 μg
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          Description
          OverviewRecombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses.
          Catalogue Number407306
          Brand Family Calbiochem®
          References
          ReferencesKohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
          Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
          Müller, U., et al. 1994. Science 264, 1918.
          Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
          Shuai, K., et al. 1993. Science 261, 1744.
          Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
          Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.
          Product Information
          FormLiquid
          FormulationSterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.
          Applications
          Biological Information
          Biological activityED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          407306

          References

          Reference overview
          Kohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
          Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
          Müller, U., et al. 1994. Science 264, 1918.
          Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
          Shuai, K., et al. 1993. Science 261, 1744.
          Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
          Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.

          Brochure

          Title
          Biologics 32.3 PDF ( 927 KB )
          Growth Factors and Cytokines Technical Bulletin

          Citations

          Title
        • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
        • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-June-2008 JSW
          DescriptionRecombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses. Expressed in and purified from E. coli.
          FormLiquid
          FormulationSterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.
          Concentration Label Please refer to vial label for lot-specific concentration
          Biological activityED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.
          Toxicity Standard Handling
          Merck USA index14, 4992
          ReferencesKohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
          Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
          Müller, U., et al. 1994. Science 264, 1918.
          Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
          Shuai, K., et al. 1993. Science 261, 1744.
          Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
          Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.
          Citation
        • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
        • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
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          Categories

          Life Science Research > Proteins and Enzymes > Other Proteins