Life Science Research
 

Cytokine, Chemokine and Other Immune Biomarker
Assays Using Luminex® Technology

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Related Resources: Analyte Quarterly | Application Notes | Webinars | Posters
Need to Assay Human IL-18?
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/IL-18-thumb.jpgLearn how to combine our Human IL-18 Singleplex Kit (HIL18MAG-66K) with three other kits to get the most out of your research!

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We have some Complement (Factors) for you!
Check out our two posters on Human Complement Panels 1 and 2 (HCMP1MAG-19K and HCMP2MAG-19K)
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/Alzheimers-poster-thumb.jpgExamining Alzheimer’s disease samples.

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Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/Examining-SLE-poster-thumb.jpgExamining SLE, JIA, and sepsis samples.

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Download the MILLIPLEX® Tips & Tricks Brochure
Tips and TricksThe Power of Multiplex Biomarker Analysis from the makers of MILLIPLEX® MAP

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New Poster and Panel
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/Human-Autoimmune-Autoantibody-poster-thumb.jpgSee our poster and learn how to use our MILLIPLEX® MAP Human Autoimmune Autoantibody Panel (Cat. No. HAIAB-10K) for your autoimmune disease serum and plasma samples.

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High Sensitivity Kits
High Sensitivity Cytokine Multiplex Kits to Fit your Needs!
Is it time for you to make the switch to high sensitivity cytokine multiplex kits? We offer the most high sensitivity analytes and formats, with quality tested reproducibility lot-to-lot. Learn more about our kits below.
  • Our original 96-well Human High Sensitivity T Cell Panel (Cat. No. HSTCMAG-28SK)
  • Our 384-well Human High Sensitivity T Cell Panel (Cat. No. HSTC384-28K) for use with the FLEXMAP 3D® instrument
  • Our Mouse High Sensitivity T Cell Panel (Cat. No. MHSTCMAG-70K)

96-well App Note | 384-well App Note | Mouse Poster
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/R-DScientist-video.jpg Learn about all of our MILLIPLEX® MAP High Sensitivity kits in this video presentation!

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Featured Customer Story
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/Vivian-Nguyen-head-shot.jpg
Dr. Vivian Nguyen, Assistant Professor, University of Arizona
Interested in how MILLIPLEX® MAP Immunology and Inflammation panels further stroke and Alzheimer’s research?
Read the SelectScience article about Dr. Vivian Nguyen’s research:
Understanding the Inflammatory Response to Stroke in the Human Brain through Mouse Models: Learn how mapping changes in the brain gives us a window to the inflammatory response

Read Article 

Read the SelectScience interview with Dr. Vivian Nguyen and Dr. Kristian Doyle, both of The University of Arizona:
Husband & Wife Duo Combating Dementia Through Neurological Research: Meet the couple combining stroke research & Alzheimer’s expertise in the hope of understanding mixed dementia.  

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Measure biomarkers of inflammation and immune response with MILLIPLEX® MAP multiplex assays, including our leading cytokine assay kits.
Acting at the recognition, activation or effector phases of an immune response, cytokines modulate the development and functional activities of T cells, B cells and myeloid cells. Quantifying cytokines is important for understanding pathological states such as inflammation, sepsis, and diseases such as autoimmune disease, cardiovascular disease, metabolic syndrome, neurological disorders and cancer.

Bring Your Immunology Biomarkers to Life with MILLIPLEX® MAP Multiplex Assays

Bead-based multiplex immunology assays enable precise, multiparametric analysis of diseases and underlying processes. Our MILLIPLEX® MAP multiplex cytokine assays, as well as other immunology kits, enable you to quantify nearly 400 analytes across several species simultaneously.

Based on Luminex xMAP® technology, our analytically validated assay kits provide:
  • Standards validated to match reference lots
  • Serum matrix for generating standard curves that accurately simulate conditions of native analyte conditions in serum or plasma
  • In-assay controls
  • Detection antibody cocktails to ensure consistent performance regardless of plex size
Some examples of the multiplex assay analytes in our portfolio are listed below.

Cytokines/Chemokines*:

IFNγ IL-13
IL-6 IL-17A
IL-8 MIP-1α
IL-1β RANTES
IL-10 TNFα
*only selected analytes listed

Other Immune Biomarkers*:

C1q C3 C3b
Granzyme B TIMP-1 FGF-2
Perforin IgM TGFβ1
MMP-9 IgE BAFF
MMP-12 G-CSF
*only selected analytes listed

Associated Intracellular Signaling Molecules*:

Akt mTOR TGFβRII
Erk GSK3α SMAD 2
JNK NFκB SMAD 3
STAT3 IκBα ATF2
*only selected analytes listed

To expand the power of your immunology research, we also offer MILLIPLEX® MAPmultiplex assays for:
Looking for antibodies for cytokines, chemokines and immune cell markers?

Visit the MilliporeSigma Inflammation and Immunology Antibodies page!
Luminex Technology

New to Multiplexing?

Click here to learn more about how Luminex technology works.
Download the Analyte Quarterly brochure for a complete, updated list of assays.

Find and Price Your Favorite Analytes & Kits —
Two Tools to Make Ordering Faster and Easier!

Interactive Product Selector

MILLIPLEX® Analyte Kit Finder

Use the kit finder below to choose the correct assays for your biomarkers of interest, so you can obtain the best quality data the first time.
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Design & Purchase Your Own Kit

Already know your analytes of choice? Start designing and purchasing your own kits now!

Choose Customizable Panels & Premixed Kits – OR – Cell Signaling MAPmates™ Assays.

Design and price your MILLIPLEX® MAP Kits.