Cell Signaling Assay Kits Using Luminex® Technology

Request Information

Related Resources: Analyte Quarterly | Application NotesPosters
Updated Wall Chart
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/MEI-Wallchart-Milliplex-Map.jpgDownload our updated Cancer and Metastasis Signaling Pathways poster to find the most highly validated kits for your cancer research.

Download Wall Chart


Download the MILLIPLEX® Tips & Tricks Brochure
Tips and TricksThe Power of Multiplex Biomarker Analysis from the makers of MILLIPLEX® MAP

Get Your Copy


What Can Our 2-plex Assays Do for You?
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/2-plex-assays.jpgWe offer 11 phospho/total 2-plex assays so that you can measure both in the same sample — in the same well! Learn how by reading our Application Note.

Download App Note


App Note
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/dna-damage.jpgRead our Application Note on our MILLIPLEX® MAP DNA Damage/Genotoxicity kit.

Download App Note


New Poster
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/Poster-Bcl-2.jpg

Learn how Bcl-2 family multiplex panels with their great sensitivity, specificity and reproducibility provide a powerful tool for studying the underlying mechanisms involving Bcl-2 family members.Learn more about 48-682MAG and 48-683MAG.

Download Poster


Measure activation of cell signaling pathways, using MILLIPLEX® bead-based multiplex assays.
Multiplexing, using the Luminex xMAP® platform, provides faster answers to your intracellular pathway questions compared to traditional Western blots, mass spectrometry, and radioactive phosphorylation assays that require large amounts of sample.

Learn more about Luminex technology

MILLIPLEX® MAP intracellular pathway multiplex kits and panels are analytically validated using the same stringent performance criteria used to manufacture our circulating biomarker kits, and they are optimized to yield maximum data from your precious samples. Our cell signaling assays enable accurate relative quantitation of both total and phosphorylated forms of signaling proteins, revealing connections and crosstalk within your pathways of interest.

Accelerate Your Signaling Research using MILLIPLEX® MAP Multiplex Assays.

Rely on the quality we build into each kit to produce results you trust. In addition to the assay specifications listed in the protocol, we evaluate other performance criteria during our validation process: cross-reactivity, dilution linearity, kit stability, and sample behavior (e.g. detectability and stability).

Our analytically validated intracellular pathway assay kits provide:
  • Stimulated and unstimulated cell lysates provided to qualify assay performance. Browse cell lysates.
  • Premixed magnetic beads to capture analytes of interest 
  • Detection antibody cocktails designed to yield consistent analyte profiles within panel
Some examples of the intracellular pathway assay kits in our portfolio are listed below.

Cell Signaling Phosphoprotein + Total 2 Plex Assays

  • Directly compare the phosphoprotein vs. total protein levels in your sample by reading them in the same well
  • Combine with other phospho/total 2 plex assays to study phosphorylation and total expression of multiple proteins simultaneously
  • Get relatively quantitative fold-increase data from your multiplexed signaling assay kits
Use the Analyte Finder to browse all Cell Signaling Phosphoprotein + Total 2 Plex Assays.

Cell Signaling Phosphoprotein and Total Multiplex Premixed Assays

  • Measure multiple phosphoproteins or total proteins within or across pathways in a single sample
  • Get relatively quantitative fold increase data from your multiplexed signaling assay kits
Use the Analyte Finder to browse all Cell Signaling Phosphoprotein + Total Multiplex Premix Assays.

MAPmates™ Phosphoprotein and Total Single Plex Kits

  • Plex up to 8 individual MAPmates™ to design your own assay using our Cell Signaling Buffer and Detection Kit (Cat. No. 48-602MAG)*
  • Plex additional MAPmates™ into existing MILLIPLEX® MAP Cell Signaling kits*
  • Use β–tubulin or GAPDH as housekeeping/loading controls by plexing into an existing MILLIPLEX® MAP Cell Signaling kit*
  • Get relatively quantitative fold increase data from your multiplexed signaling assay kits
Learn more about MAPmate™ assays

To expand the power of your intracellular research, we also offer circulating MILLIPLEX® MAP multiplex assays for:
 
Merck:/Freestyle/BI-Bioscience/Protein-Detection/bmia-images/luminex-magpix2.jpgNew to multiplexing?
Click here to learn more about how Luminex technology works.

Download the Analyte Quarterly brochure for a complete, updated list of assays.

Find and Price Your Favorite Analytes & Kits —
Two Tools to Make Ordering Faster and Easier!

Interactive Product Selector

MILLIPLEX® Analyte Kit Finder

Use the kit finder below to choose the correct assays for your biomarkers of interest, so you can obtain the best quality data the first time.
1
Please select the species reactivity:

2
Please select the research area:

3
Please select your protein of interest:

 

Design & Purchase Your Own Kit

Already know your analytes of choice? Start designing and purchasing your own kits now!

Choose Customizable Panels & Premixed Kits – OR – Cell Signaling MAPmates™ Assays.

Design and price your MILLIPLEX® MAP Kits.