Filtration Methods for Chromatography Applications

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Filter Your Samples and Mobile Phases for Better Analysis Results.

To satisfy researchers’ demands for more information about their samples, manufacturers of HPLC, UHPLC, LC/MS and GC/MS instrumentation are constantly developing new technologies that improve sensitivity and decrease processing time. Accompanying these new technologies is the need for higher purity samples and cleaner mobile phases.

Particulates in the sample can interfere with analysis by adsorbing some analytes of interest, causing low analyte recoveries in liquid, gas and ion chromatography. Therefore, filtering samples is extremely important before performing your downstream analysis. Proper filtration of samples, solvents and buffers not only generates higher quality, more consistent results, but it also increases instrument uptime and prolongs column life. MilliporeSigma provides filtration tools that enable high quality analysis.