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Strasbourg area, France
ADC | MilliporeSigma

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Wednesday, May 22, 2019

M Lab™ Collaboration Center, Molsheim

You are invited to participate in MilliporeSigma’s ADC & Bioconjugation Symposium. Learn, share and discuss today’s advancements with your peers and subject matter experts of the industry.

This one-day event will include:

  • Industry experts presenting advancements in ADC / Bioconjugation development and drug-linker technologies
  • Innovative ADC processing showcasing the latest technology at our M Lab™ Collaboration Center
  • Opportunities to network with experts and peers during refreshment breaks, lunch and dinner

Register here

Mercrobe EMD Millipore

Agenda*

Wednesday, May 22, 2019

9:30 - 10:00Registration and morning coffee
 
10:00 - 10:05Welcome
 Robert Guagliardo, MilliporeSigma
 
10:05 - 10:20Opening remarks from the symposium chair
 Dr. Vincent Turula, Pfizer
 
Latest advances in drug development and linker-payload technologies
 
10:20 - 10:50Site-specific and stoichiometric functionalization of antibodies with transglutaminase
 Prof. Roger Schibli, ETH Zurich
 
10:50 - 11:20PBD payloads for ADC - Current clinical status, technical challenges and opportunities
 Dr. Francois D‘Hooge, Consultant
 
11:20 - 11:30Break
 
11:30 - 12:00Chemo-enzymatic glycan conjugation of toxic payloads provides ADCs with superior therapeutic index
 Dr. Marloes Wijdeven, Synaffix BV
 
12:00 - 12:30Amanitin-based ADCs as new therapeutic modalities for cancer therapy
 Dr George Badescu, Heidelberg Pharma AG
 
12:30 - 13:00Modernizing ADC control strategies
 Dr. Nathan Ihle, Immunomedics, Inc.
 
13:00 - 14:00Lunch
 
Technology insights, processing and services
 
14:00 - 14:30Accurate and robust methods for product characterization of unconjugated mAbs and conjugated ADCs
 Dr. Daniel Galbraith, MilliporeSigma, BioReliance
 
14:30 - 15:00Characterization of monodisperse oligo ethylene glycol ADC linkers
 Dr. Tobias Haag, MilliporeSigma
 
15:00 - 15:30ADC process development and case studies on the impact of small molecule impurities on the conjugation process and the clearance of organic solvent by TFF
 Dr. Maxime Lampilas, Sanofi
 
15:30 - 16:00Process understanding and automated processing in development to ensure first pass manufacturing success of ADCs
 Lisa McDermott, MilliporeSigma
 
16:00 - 16:15Poster presentation and afternoon coffee:
Demonstration of solvent compatibility and extractables profile for use of Mobius® assemblies in ADC processing
 MilliporeSigma
 
16:15 - 16:30Poster presentation and afternoon coffee:
Mobius® mixing studies in ADC processing
 MilliporeSigma
 
16:30 - 17:00M Lab™ Collaboration Center tour
 MilliporeSigma
 
17:00 - 17:15Wrap-up and closing remarks
 
18:00 - 21:00Post-event activity, reception and dinner in Strasbourg
 
21:00End of the event

* Agenda subject to change. Attendance to the ADC & Bioconjugation Symposium is limited and available to pharma/biopharma manufacturers only. The offer does not extend to any company that provides products or services to the pharma/biopharma industry. We reserve the right to revoke or refuse participation at any times. The event is free of charge, though registration is required. Refreshments, lunch and dinner are provided courtesy of Merck KGaA, Darmstadt, Germany. Travel costs, hotel accommodations and any other costs incurred are at the expense of the attendees.

Venue Information
M Lab™ Collaboration Center, Molsheim
MilliporeSigma M Lab™

The Symposium will take place at our M Lab™ Collaboration Center in Molsheim, France:

Millipore SAS
M Lab™ Collaboration Center
39 route industrielle de la Hardt
67120 Molsheim, France
(region of Strasbourg)

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Learn about our M Lab™ Collaboration Centers