EZHCMRN-57K | Human Chemerin ELISA

EZHCMRN-57K
96-well strip plate  
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      Overview

      Replacement Information

      Key Spec Table

      Analytes Available Species Reactivity Key Applications Detection Methods
      Chemerin H ELISA Colorimetric, Fluorescent
      Description
      Catalogue Number EZHCMRN-57K
      Description Human Chemerin ELISA
      Background Information Chemerin, an 18 kDa protein and a natural ligand of GPCR Chemokine-like Receptor 1, acts as both an adipokine involved in adipocyte differentiation and a chemoattractant in the recruitment of immune response cells. Most recent publications have demonstrated that chemerin is secreted from differentiated 3T3-L1 cells and human adipocytes, and is normally expressed at low levels in pre-adipocytes with a dramatic increase in expression during differentiation into adipocytes. As an adipokine, circulating levels of chemerin correlate with body mass index (BMI), plasma triglyceride concentrations, and blood pressure. At the same time other studies have shown that, as a chemokine, chemerin plays a crucial role in the co-localization of blood natural killer cells, dendritic cells and macrophages to areas of inflammation, initiating an immune response. Consequently, these observations suggest that chemerin may be an important biomarker in understanding both the pathogenesis of metabolic syndrome and the role of inflammation in eliciting an immune response.
      References
      Product Information
      Detection method Colorimetric Fluorescent
      Precision, %
      • Intra-assay: 5%
      • Inter-assay: 6%
      Applications
      Application This Human Chemerin ELISA is used to measure & quantify Chemerin levels in Metabolism & Endocrine & Cancer research.
      Key Applications
      • ELISA
      Application Notes This is a 3.5-hour assay at room temperature requiring 20 ul human serum, plasma, and culture samples (1:5 dilution is required for human serum or plasma samples)
      Biological Information
      Species Reactivity Human
      Analytes Available
      • Chemerin
      Accuracy
      • 91 - 100%
      Physicochemical Information
      Sensitivity
      • 1.6 ng/mL
      Linearity of Dilution Contact Technical Support
      Standard Curve Range
      • 1.6 - 100 ng/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size 96-well strip plate
      Transport Information
      Supplemental Information
      Specifications